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A Comparative Study For Antioxidant And Anticancerous Potential Of Moringa Oleifera Leaves Extract Against Cervical Cancer Hela Cells

Author(s) Fahad Khan
Country India
Abstract A number of pharmacological properties attributed to several parts of Moringa oleifera have been widely accepted by both Unani and Ayurvedic practices of medicines. Therefore, the current study is projected to explore the antioxidant and anticancerous potential of various sequentially extracted fractions of Moringa oleifera leaves (including aqueous, ethanolic, methanolic and hexane extract) against HeLa cervical cancer cells. Our result showed that among different fractions of Moringa oleifera, MMLE (Moringa oleifera leaves methanolic extract) extract has higher phenolic content and also exhibited significantly more radical scavenging (DPPH and Superoxide) and antioxidant (FRAP) capacity. Moreover, MMLE also exhibited significantly higher anticancerous potential by reducing cell viablility in cervical cancer HeLa cell line. Our results support the potent antioxidant and anticancerous activity of methanolic extract of Moringa oleifera which adds one more positive attribute to its known pharmacological importance. Further in vivo studies are needed to utilize these experimental findings towards developing a potent lead compound against cervical cancer cells.
Keywords Moringa oleifera, Antioxidant, anticancer, apoptosis, Cervical cancer, HeLa
Field Medical / Pharmacy
Published In Volume 1, Issue 2, October 2020
Published On 2020-10-03
Cite This A Comparative Study For Antioxidant And Anticancerous Potential Of Moringa Oleifera Leaves Extract Against Cervical Cancer Hela Cells - Fahad Khan - IJLRP Volume 1, Issue 2, October 2020.
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