Commissioning of the Mobius3D Independent Dose Verification System for Linear Accelerator

Priya Jacob

doi:10.5281/zenodo.14769786

Commissioning of the Mobius3D Independent Dose Verification System for Linear Accelerator

Author(s)	Priya Jacob
Country	United States
Abstract	Ensuring the accuracy of radiation therapy treatment plans is essential for patient safety and treatment efficacy and a secondary independent dose verification is an important for quality control. Mobius3D utilizes reference beam data and a collapsed cone convolution algorithm to calculate three-dimensional (3D) patient dose and automatically analyze dose-volume histograms. To verify its accuracy, we compared Mobius3D calculations with ion chamber measurements in an RW3 Slab Phantom for 50 helical intensity-modulated radiation therapy (IMRT) plans,1 yielding an average dose difference ratio of −0.2 ± 0.6%. Additionally, 100 treatment plans across various anatomical sites were evaluated by comparing Mobius3D calculations with those from the treatment planning system (TPS), focusing on dose indices and 3D gamma passing rates. Based on these results, action and tolerance levels for the planning target volume (PTV) at each treatment site were determined as μ ± 2σ and μ ± 3σ, respectively. The average gamma passing rate using a 3%/3 mm criterion was 99.8 ± 0.35%. We also established action and tolerance levels for both the PTV and organs at risk across all treatment sites. Mobius3D11 provides an accurate secondary dose verification system that can be efficiently commissioned after installation. Before clinical implementation, it must be commissioned using patient-specific treatment plans from each institution to validate calculation accuracy and establish site-specific tolerances. Before clinical use, the Mobius3D system needs to be commissioned using the treatment plans for patients treated in each institution to determine the calculation accuracy and establish tolerances for each treatment site and dose index.
Keywords	commissioning, independent verification, Mobius3D, tolerance, Linear Accelerator, Varian TrueBeam.
Field	Engineering
Published In	Volume 3, Issue 6, June 2022
Published On	2022-06-08
Cite This	Commissioning of the Mobius3D Independent Dose Verification System for Linear Accelerator - Priya Jacob - IJLRP Volume 3, Issue 6, June 2022. DOI 10.5281/zenodo.14769786
DOI	https://doi.org/10.5281/zenodo.14769786
Short DOI	https://doi.org/g83kv6

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Commissioning of the Mobius3D Independent Dose Verification System for Linear Accelerator

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